At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

US004 PA Malvern - 200 Great Valley Pkwy

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Experienced Scientist, Large-Scale Development & Operations Downstream to be in Malvern, PA.

Purpose: The candidate for this position will work as a member of a small team to perform scale-up/scale-down development of therapeutic biologics with strong emphasis on API proteins within the Large-Scale Development & Operations downstream (DSP) group in Malvern, PA. The candidate’s primary responsibilities will include pilot-scale DSP operations execution, DSP data acquisition and modeling, and optimizing the process steps to be representative of the target process scale to ensure right first-time technical transfers.

You will be responsible for:

• Pilot-scale and laboratory work with chromatographic purification and several types of filtration systems
• Record and analyze data, verify data integrity and accuracy, and report/summarize findings to the project development teams
• Design experiments to optimize DSP operations within the Large-Scale Development & Operations DSP group to ensure that they are representative of internal and external manufacturing sites
• Draft technical documents, SOPs, and work instructions
• Work in a team environment as well as contributing individually to meet project timelines and objectives

Qualifications / Requirements:

Education:

• Minimum of BS in Chemical or Biochemical Engineering or related degree with at least 4 years of relevant experience is required.

Qualifications:

Required:

• Knowledge of and hands-on experience with DSP purification (chromatography, filtration) of protein therapeutics (such as antibodies) is required.
• Experience with scale-up/down technical transfers of DSP processes, and/or execution at pilot or manufacturing scales for biologics manufacture is required.
• The candidate must be highly organized and capable of managing/pursuing multiple projects with minimal supervision.
• Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required.

Preferred:

• Exposure to analytical method development for in-process methods is preferred.
• Experience in fostering team collaboration, motivating team members, and achieving project goals within a small group setting as a matrix leader is preferred.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

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Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.