At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

US026 PA Spring House - 1400 McKean Rd

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Lentivirus Upstream Process Experienced Scientist to be in Spring House, PA.

You will be responsible for:

• Acts as a developing individual contributor in the execution of Biotherapeutic projects to support development programs.
• Assists with the design of lead biologic candidates and works to implement next generation targeting technologies for a variety of Biotherapeutic modalities.
• Independently designs experiment/analyses based on interpretations and integration of emerging literature or other sources.
• Assists in developing recommendations for improving standard procedures.
• Contributes to the preparation and submission of technical reports, patent applications, protocols and manuscripts with detailed outcomes and results of research findings as relevant.
• Coaches more junior colleagues in techniques, processes and responsibilities.
• Understands and applies Johnson & Johnson’s Credo and Leadership Imperatives in day-to-day interactions with team.
• Integrate into the upstream process development team and focus on lentiviral vector-based products such as cell and gene therapy within DPDS, API.
• This role involves working with the development team leads and scientists, taking on an individual role of performing, maintaining, and monitoring cell cultures while engaging in a team role to meet development objectives with some supervision.
• You will contribute to experiment planning to scale up viral vector-based processes from shake flasks to bioreactors, assist in identifying and establishing process parameters and ranges, performing planned experiments, optimizing upstream cell culture process steps, perform data analysis for early and late-stage products, and technology transfer the process to GMP clinical or commercial manufacturing sites.
• May also perform side studies related to media optimization, technology evaluation, and other cell culture related activities as needed.

Qualifications

Required:

• A Bachelor's degree Chemical Engineering, Biomedical Engineering, Biological Sciences, Chemistry, Biochemistry, or other equivalent and background with at least 3-4 years of relevant industry experience is required (or a Master's degree with at least 2 years of experience is preferred).
• Broad knowledge in upstream process development and good understanding of cell culture parameters. Hands-on experience with aseptic techniques, cell culture in shake flasks, Wave bioreactors, and bioreactor systems, and cell counting/monitoring methods is required.
• Candidate needs to be highly organized, meticulous, and capable of handling/pursuing multiple projects in parallel with limited guidance.
• Strong analytical problem-solving skills for developing creative, innovative solutions, and meeting project objectives is required.
• Ensure compliance with all relevant safety and quality standards.
• Experience maintaining accurate and detailed records of experimental procedures, data, and results in a well-organized electronic lab notebook, ensuring reproducibility, accessibility to team members, and compliance with any regulatory requirements.

Preferred:

• Previous experience with upstream process development of viral vector based products is highly preferred.
• Familiarity with analytical methods typically used in the manufacture and characterization of viral-based products.
• Excellent leadership, communication, and interpersonal skills with the ability to operate effectively in a dynamic work environment and collaborate with cross-functional teams is preferred.
• Excellent presentation, verbal communication, and scientific/technical writing skills is preferred.
• Ability to make timely decisions and operate efficiently in times of ambiguity is preferred.

Other:

• This role will be based in Spring House, PA and may require up to 10% travel. Occasional weekend work is required.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.