Johnson & Johnson is seeking a POSTDOCTORAL FELLOW – CELL THERAPY PROCESS DEVELOPMEN to join a team of talented postdocs in the Biotherapeutics Development & Supply, Cell Therapy API department. This position is located in Spring House, PA!

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Janssen R&D Discovery, Product Development, & Supply (DPDS) Postdoctoral Fellowship Program helps early career scientists gain the training and experience needed to further their careers, while addressing the needs of global healthcare. Janssen DPDS Postdocs work side-by-side with Janssen scientists on innovative research projects and have the opportunity to present and publish their work. They also learn the functional role of scientists in the pharmaceutical industry and receive valuable career advice from mentors while building a network of professional contacts and developing the skills needed to advance their careers.

The candidate will join the API Cell Therapy Process Development team where they will investigate/optimize novel metabolic and process parameters within the autologous manufacturing process to produce more potent and durable CAR-T cells for oncology indications. In addition to T cell metabolism work, the Postdoctoral fellow will have the opportunity to learn and participate in the development of next generation autologous cell therapy manufacturing process design.

THE CANDIDATE’S RESPONSIBILITIES WILL INCLUDE:

• Independently design and execute experiments

• Data analysis and interpretation, defining next steps

• Cross-functional collaboration and communication, presenting results, preparing manuscript(s)

• Development, training, conferences, internal meetings & symposia

QUALIFICATIONS

REQUIRED MINIMUM EDUCATION

• PhD Required Years of Related Experience: 0-1

REQUIRED KNOWLEDGE, SKILLS, AND ABILITIES:

• Microsoft Excel, Spotfire, GraphPad, FlowJo

• Experience with Western blots, RT-PCR

                       PREFERRED AREA OF STUDY:

• Biological Sciences, Immunology, Cellular Metabolism, Biomedical Engineering

PREFERRED KNOWLEDGE, SKILLS AND ABILITIES:

• A working background in T cell biology and metabolism with hands on experience in T cell culture and gene engineering

• Knowledge and experience in autologous CAR-T cell therapy

• Experience with analytical assays including flow cytometry, ELISAs, cytokine release assays, mitochondrial membrane potential assays and metabolic profiling using Nova Bioprofile or BGA

• Must have excellent communication, interpersonal and collaborative skills and demonstrate deep intellectual curiosity

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.]

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