At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist, CAR Screening and Lead Selection, Cell and Genetic Medicines to be in Spring House, PA.

Summary:

We are seeking a highly motivated and experienced Senior Scientist to join our Cell Therapy team. In this role, you will play a key part in advancing our cutting-edge cell therapy programs by driving the development, optimization, and execution of experiments to enhance the therapeutic potential of our CAR T cell products, in addition to collaborating with cross-functional teams to support discovery activities. The ideal candidate will have a strong background in immunology, or related fields, with demonstrated experience in cell therapy focused assay development and execution. This role is a unique opportunity to contribute to scientific advancements that have the potential to revolutionize healthcare. Come join us and become part of a fast-paced team working to achieve curative responses in patients with cancer by building best-in-class cell therapies.

You will be responsible for:

• Design, develop, and execute T cell-based experiments
• Analyze data from in vitro studies, providing insights and recommendations to drive decision-making.
• Collaborate closely with cross-functional teams to ensure alignment with project goals.
• Contribute to the preparation of technical reports and data packages.
• Aid in the mentorship and training of junior scientists and research associates, fostering a collaborative and innovative environment.
• Stay current on the latest scientific and technological advancements in cell therapy and related fields, and incorporate new knowledge into ongoing projects.
• Present findings and updates to senior leadership, internal stakeholders, and external partners as required.
• Ensure compliance with all relevant safety and quality standards.
• Maintain accurate and detailed records of experimental procedures, data, and results in a well-organized lab notebook, ensuring compliance with company standards and regulatory requirements.
• Ensure that all experiments are properly documented, reproducible, and accessible to team members and collaborators.

Qualifications:

• Ph.D. in Cell Biology, Immunology, Molecular Biology, or a related field with 3+ years of relevant postdoctoral or industry experience; OR a BS or MS with 4-6 years of equivalent experience in a biopharmaceutical or biotechnology setting is required.
• Strong expertise in cell-based therapy research, including experience with CAR T or similar platforms is required.
• Hands-on experience with cell culture, viral transduction, cytotoxicity assays (Incucyte-based preferred) and flow cytometry is required.
• Solid understanding of immunology and tumor biology, with experience in preclinical models (in vitro and in vivo) is preferred.
• Proven ability to lead scientific projects and deliver high-quality results and recommendations in a fast-paced, collaborative environment.
• Experience in preparing and reviewing technical reports is preferred.
• Demonstrated ability to analyze complex biological data sets, synthesize results, and provide actionable insights to guide experimental decisions and project strategies is required.
• Excellent communication and presentation skills, with the ability to convey complex scientific information to diverse audiences is required.
• Strong problem-solving skills, attention to detail, and a proactive, innovative mindset.
• Prior experience with automation and high-throughput screening for cell-based assays is preferred.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected vertebras and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

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Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.