At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biological Research

Job Category:

Scientific/Technology

All Job Posting Locations:

US026 PA Spring House - 1400 McKean Rd

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

An internal pre-identified candidate for consideration has been identified. However, all applications will be considered.

We are searching for the best talent for Sr. Scientist Oncology Discovery to be in Spring House, PA.

The Senior Scientist will:

• Design, implement, analyze, and interpret in vitro assays to interrogate CAR T cell therapy performance

• Innovate and improve current methodologies to improve therapeutic activity of cell therapy products

• Collaborate effectively with internal and external colleagues to get critical feedback and advance key findings

• Distill complex ideas into practical next steps

• Communicate results in writing and oral presentations to enable key decisions

• Keep accurate and timely records of all experiments

• Provide mentorship to associate team members, and promote professional development

• Improve next generation cell therapy products for cancer patients.

• Lead discovery programs and effectively collaborate with colleagues in other functional areas.

• Responsible for developing innovative mechanisms to improve CAR T cell therapy

Qualifications:

• PhD degree with post-doctoral and/or industry experience in immunology or a related discipline.

• Ability to design, perform and interpret in vitro and in vivo CAR-directed cell therapy experiments to assess cytotoxicity, cytokine production, cell proliferation, and metabolic profiles

• Applied experience with multiparameter flow cytometry design and analysis

• Ability to work independently, and manage multiple projects and workstreams simultaneously

• Ability to contribute to various projects outside of their own, and collaborate with team members from all relevant functions

• Ability to keep up-to-date with the literature and be a thought leader in cell therapy

• Ability to mentor and develop Ph.D. and non-Ph.D. scientists

• Ability to stay organized, pay attention to details, plan for complicated long-term projects, and maintain detailed records

• Demonstrate clear and professional verbal and written communication

• A positive, can-do attitude, the ability to work well within a cross-functional team, and the ability to design and implement critical assays to study human CAR T cell biology

Preferred:

• Hands-on experience working with human primary T cells and CAR T cells

• Strong foundation in immunology with deep understanding of T cell biology, signaling, metabolism, and effector function

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ( ra-employeehealthsup@its.jnj.com ) or contact AskGS to be directed to your accommodation resource.

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.