Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

Our In Vivo Pharmacology group in Lake County, IL has an opening for a motivated in vivo pharmacologist who is dedicated to the discovery and development of innovative treatments. The position involves working with both small molecule and biological therapeutics, with a focus on diseases of aging such as mitochondrial, metabolic, peripheral organ diseases, and fibrotic disorders. Primary responsibilities include independently executing, reporting, and troubleshooting in vivo pharmacology studies based on previous hands-on experience and foundational theoretical knowledge.

The scientist will work on preclinical in vivo models in mice and rats for age-related diseases (e.g., fibrosis, immune, kidney, metabolic, or cardiovascular) as well as mechanism of action and Pharmacokinetics/ Pharmacodynamic (PK/PD) studies.

The position requires interaction with in vivo / in vitro biology, translational/ biomarkers, PK and medicinal chemistry teams to advance therapeutic agents through the R&D pipeline.

Responsibilities:

• Acts as Study Leader/Coordinator for assigned studies and demonstrates proficiency in general in vivo procedures in mice and rats including dosing

• Maintains competency in all aspects of rodent handling and treatment dosing of small molecules and biologics in mice and rats

• Experience with ELISA / MSD/ /multiplex/ biochemical assay methods/ Western Blots/ qPCR and/or immunohistochemistry of paraffin/frozen sections is desired

• Develops and optimizes new methods/techniques to generate reliable and reproducible data in a timely manner. Experience in ex vivo processing of tissues (homogenization, RNA extraction) and analyses (ELISA, MSD, flow cytometry, WB, PCR, biochemical assays, multiplex platform) is desired

• Using an electronic notebook to maintain proprietary study records

• Working closely with his/her supervisor to schedule and prioritize workload to manage several tasks simultaneously

• Exhibiting excellent communication skills and the ability to present data clearly and thoroughly in both one-on-one interactions and group meetings

• This is an on-site laboratory position

Qualifications

Position will be hired based on level of education and experience

• Bachelor’s Degree or equivalent education with typically 5 years of experience, or Master’s Degree or equivalent education with typically two years of experience.
• Proven expertise with design and execution of studies utilizing in vivo / ex vivo techniques in rodents is required
• Experience with drug formulation and administration to rodents via SC, PO, IP, and IV routes
• Experience utilizing in vivo / ex vivo techniques in rodents. This includes physiological measurements, tissue collection, and analysis by biochemical or histological methods. Experience with ELISA / MSD / Western Blots/ biochemical assays, flow cytometry and/or immunohistochemistry is desired
• Strong problem-solving skills
• Familiarity with data graphing, data analysis, presentations, and statistical software (e.g. Microsoft Office Suite, Prism) is necessary
• Good communication skills and willingness to work with a cross-functional team of researchers is essential

Key Leadership Competencies

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance
• Learns fast, grasps the 'essence' and can change the course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Embraces the ideas of others, nurtures innovation and manages innovation to reality

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.