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Senior Scientist, MS&T Downstream

Bristol Myers Squibb

Bristol Myers Squibb

Senior Scientist, MS&T Downstream

Devens, MA
Full Time
Paid
  • Responsibilities

    Working with Us

    Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

    Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

    Position Summary

    The Senior Scientist – Downstream in Manufacturing Sciences & Technology supports the commercial and late-stage clinical manufacturing of biopharmaceuticals in the area of purification and primary recovery. The successful candidate will be a subject matter expert and key contributor to a highly technical, diverse, and collaborative team of scientists and engineers. MS&T scientists and engineers contribute to cross-functional teams to meet highly visible business objectives. The position offers the opportunity to interface with Manufacturing, Manufacturing Support, Process Development, Quality Assurance, Analytical, and Global Regulatory Sciences groups.

    Key Responsibilities

    Responsibilities include but are not limited to:

    • Support commercial and late-stage clinical manufacturing process by providing technical expertise for investigation of downstream process deviations, root cause analysis, CAPAs, and process improvements.

    • Support for downstream process technology transfer, process validation, and CMC documentation preparation.

    • Leading technical studies. Following GLP/GMP procedures to design and execute experiments to solve process-related manufacturing investigations or to enable the technology transfer of new processes to larger scale manufacturing through the use of laboratory and pilot scale-down models in protein chromatography, viral inactivation, viral filtration, ultrafiltration/diafiltration, membrane filtration, depth filtration, and centrifugation.

    • Documentation of experimental data and results, data verification, interpretation of data with respect to the laboratory protocol and the manufacturing process, and preparation of final reports to summarize the findings.

    • Support downstream regulatory filing preparation, agency inspection, and agency inquiry responses.

    • Effective collaborations with Manufacturing, Manufacturing Support, Process Development, Quality Assurance, Analytical and Global Regulatory Sciences groups. Strong communication and technical writing skills are required.

    • Evaluation of new process technologies.

    Qualifications & Experience

    • BS or MS or PhD in Chemical/Biochemical Engineering or Biochemistry related field. BS or equivalent with a minimum 5 years relevant industrial experience, MS or equivalent with minimum of 4 years relevant industrial experience, Ph.D. with 0-4 years of relevant experience.

    • Solid scientific understanding of protein purification and protein stability is required. Lab experience with AKTA purification and ultrafiltration/diafiltration operations is preferred.

    • Critical qualities include a high level of scientific curiosity and critical thinking ability, good verbal/written communication skills to interface with multi-disciplinary teams.

    If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

    Uniquely Interesting Work, Life-changing Careers

    With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

    On-site Protocol

    Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

    BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

    BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

    BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

    Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

  • Industry
    Pharmaceuticals
  • About Us

    Bristol Myers Squibb is a leading global biopharma company focused on discovering, developing and delivering innovative medicines for patients with serious diseases in areas including oncology, hematology, immunology, cardiovascular, fibrosis and neuroscience. Our employees work every day to transform patients’ lives through science.