Job Description

The Head of Compliance & Ethics will play a critical strategic role in building and leading the company’s compliance and ethics program, reporting to the Chief Legal Officer & General Counsel and working closely with the Executive Team. You will ensure that all corporate activities—especially those related to clinical development, medical affairs, and commercial operations—adhere to the highest legal and ethical standards. You will work cross-functionally to embed compliance into everyday operations, mitigating risk while fostering a culture of ethics and integrity across the organization as we scale and approach potential commercialization.

Key responsibilities:

• The Head of Compliance & Ethics serves as the key contact on issues relating to the implementation of and compliance with Bicycle’s Code of Business Conduct & Ethics and related policies
• Develop, implement, and maintain a comprehensive compliance and ethics program, ensuring alignment across all functions, including clinical development, medical affairs, and commercial teams
• Ensure compliance with global regulatory requirements, industry standards, and internal policies across all functions
• Partner with cross-functional teams to embed ethical decision-making into clinical trials, product development, and commercial strategies
• Lead compliance training programs tailored to the unique needs of the company
• Oversee risk assessments and internal audits/monitoring to proactively identify and address compliance vulnerabilities
• Collaborate with leadership to integrate compliance into strategic decision-making processes
• Manage reporting, investigations, and resolution of compliance violations
• Working closely with Regulatory Affairs teams, stay up to date with international and regional laws and regulations and ensure the company's adherence to these requirements

Qualifications

• Proven experience in compliance leadership within the biotech or pharmaceutical industry
• Strong understanding of compliance requirements, including across clinical development, medical affairs, and commercial operations
• Exceptional strategic thinking, with the ability to build and integrate compliance programs across multiple functions
• Demonstrated ability to work cross-functionally and influence diverse teams and leadership
• Strong knowledge of global regulatory and compliance standards (e.g., FDA, EMA) and healthcare laws
• Excellent leadership, communication, and interpersonal skills

Additional Information

• Flexible working environment
• Competitive reward including annual company bonus
• Medical, dental, and vision insurance for eligible employees and their families with 100% of the premiums covered by the Company
• Health and Dependent Care Flexible Spending Accounts
• 401(k) plan with a 4% Company match and immediate vesting
• Eligibility to accrue up to 23 paid time off days per full year worked, plus the option to buy up to 5 additional days
• Employee assistance program
• Employee recognition schemes
• 10 Company holidays
• Competitive Family Leave Policy
• Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.