Job Description

Eurofins PSS is seeking a talented in vitro biologist that can contribute to our efforts in Global Therapeutics-Companion Animal Discovery. The group partners with therapeutic areas and project teams to design novel substrate screening assays and build robust testing funnels for a variety of therapeutic approaches that improve diseases or conditions in companion animals (cats, dogs, horses).

The successful candidate should have at least 1 year of relevant experience executing cell-free and cell-based in vitro screens for evaluation of substrate (biotherapeutics and small molecule). Experience with developing and/or optimizing plate-based cellular assays and analyzing data from in vitro screens are a plus. Excellent communication, organizational and interpersonal skills are essential.

POSITION RESPONSIBILITIES:

• Develop, optimize, and execute cell-free (e.g., ligand binding, biochemical) and cell-based in vitro screening assays for assessing substrate potency (small molecule and biotherapeutics)
• Perform immune-based techniques such as AlphaLISA, Luminex, ELISA, flow cytometry, immunohistochemistry, etc.
• Apply a variety of cellular and molecular techniques to develop cellular models of disease for veterinary species
• Cell culture and aseptic technique; maintenance of primary and immortalized/recombinant cell lines
• Isolation of primary cells from tissues or whole blood (PBMC isolation)
• Experience with RNA extraction and qPCR techniques a plus
• Data analysis and interpretation; maintenance of an accurate lab notebook and presentation of data at team meetings
• Collaborate across multiple scientific disciplines

Qualifications

EDUCATION AND EXPERIENCE:

• Educational background: BS or MS (molecular or cellular biology, immunology, or related field)
• Training or experience in biological sciences preferred
• Experience in developing, optimizing, and executing cell-based in vitro screens is highly desirable
• Experience with assay automation a plus
• Experience with analysis and interpretation of data from in vitro screens (e.g., IC50 determination)
• Experience in flow cytometry and live-cell imaging a plus
• Self-starter, able to prioritize work and work efficiently with minimal supervision
• Excellent verbal/written communication, organizational and interpersonal skills
• Computer skills required: Microsoft Word, Excel, Outlook
• Experience with GraphPad Prism or similar graphing software a plus

Additional Information

Eurofins Lancaster Laboratories Professional Scientific Services® (PSS) is a global, award-winning insourcing solution that places our people at our clients’ site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries.

We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client’s quality systems and equipment.

Eurofins USA PSS Insourcing Solutions is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.