Scientist - Antibody/Protein Engineering

Eurofins USA Discovery Services

Scientist - Antibody/Protein Engineering

Saint Charles, MO
Full Time
Paid
  • Responsibilities

    Job Description

    Essential Duties and Responsibilities:

    • Performs work in a laboratory setting, meeting the physical job requirements of a lab role
    • Conducts production assays primarily in Biotherapeutics Discovery, but may support other Services and activities based on business needs
    • Develops and performs assays for Biotherapeutics discovery applications
    • Writes and maintains SOPs as required
    • Develops new methods supporting project teams both internally and externally for large molecule discovery, characterization, and optimization
    • Performs Troubleshooting and Maintenance of equipment employed in the screening process (e.g. liquid handlers, stackers, plate washers, readers)
    • Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
    • Provides solutions to complex problems, identifies and initiates process improvements
    • Maintains high data quality and reproducibility
    • Performs data and report QC review within the department, and may support study director activities
    • Takes ownership of client projects with minimal supervision
    • Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems
    • Completes required training and supports 100% of Employee Health and Safety requirements
    • Demonstrates proficiency with care and maintenance of lab equipment and department assets
    • Conducts responsible use of confidential IT and business systems, as required
    • Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting
    • Supports unit goals and demonstrates Eurofins’ competencies, as defined in the job plan
    • Provides training to colleagues and external end users, when required
    • Contributes to scientific community, and site research and development objectives
    • Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives
    • Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines
    • Routinely communicates project updates to internal and external clients
    • Performs other duties, as assigned
  • Qualifications

    Qualifications

    Basic Minimum Qualifications (BMQ):

    • Direct experience with construct design (antibody and non-antibody proteins) in a contract research organization or industry laboratory for large molecule discovery applications
    • Direct experience with antibody discovery methodology
    • Familiarity with concepts of extracting data from the literature and FTO
    • Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
    • Good communication and interpersonal skills
    • Experience working in a Quality Management System
    • Ability to work in the U.S. indefinitely without sponsorship

    Education/Experience (BMQ):

    • B.S. with 5 years relevant experience
    • M.S. with 3 years relevant experience
    • Ph.D. with 1 year relevant experience
    • Or an equivalent of education and experience

    ** Additional preferences:**

    • Scientific expertise with different types of protein design, optimization and production
    • Scientific expertise in protein production, purification and QC of proteins (antibody and non-antibody)
    • Scientific expertise with construct design for cell line development
    • Familiarity with mining public or non-public resources of antibody analysis (immunogenicity, stability, solubility etc.) for antibody engineering and design
    • Background knowledge of sequence-structure-function correlation
    • Experience in small team leadership and project management
    • Experience in leading and delivering results in R&D or innovation programs

    Supervisory Responsibility:

    • 0 – 2 junior Scientists – ability to lead cross-functional projects in direct or dotted-line responsibility.

    Additional Information

    The position is full-time, Monday-Friday, 8 a.m.-5 p.m., with overtime as needed. Candidates within a commutable distance of St. Charles, MO are encouraged to apply.

    • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
    • Life and disability insurance
    • 401(k) with company match
    • Paid vacation and holidays

    Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.